Residual Detergent Detection Method for Nondestructive Cytocompatibility Evaluation of Decellularized Whole Lung Scaffolds
نویسندگان
چکیده
منابع مشابه
Tissue Specificity of Decellularized Rhesus Monkey Kidney and Lung Scaffolds
Initial steps in establishing an optimal strategy for functional bioengineered tissues is generation of three-dimensional constructs containing cells with the appropriate organization and phenotype. To effectively utilize rhesus monkey decellularized kidney scaffolds, these studies evaluated two key parameters: (1) residual scaffold components after decellularization including proteomics analys...
متن کاملRevascularization of decellularized lung scaffolds: principles and progress.
There is a clear unmet clinical need for novel biotechnology-based therapeutic approaches to lung repair and/or replacement, such as tissue engineering of whole bioengineered lungs. Recent studies have demonstrated the feasibility of decellularizing the whole organ by removal of all its cellular components, thus leaving behind the extracellular matrix as a complex three-dimensional (3D) biomime...
متن کاملCan stem cells be used to generate new lungs? Ex vivo lung bioengineering with decellularized whole lung scaffolds.
For patients with end-stage lung diseases, lung transplantation is the only available therapeutic option. However, the number of suitable donor lungs is insufficient and lung transplants are complicated by significant graft failure and complications of immunosuppressive regimens. An alternative to classic organ replacement is desperately needed. Engineering of bioartificial organs using either ...
متن کاملDecellularized scaffolds in regenerative medicine
Allogeneic organ transplantation remains the ultimate solution for end-stage organ failure. Yet, the clinical application is limited by the shortage of donor organs and the need for lifelong immunosuppression, highlighting the importance of developing effective therapeutic strategies. In the field of regenerative medicine, various regenerative technologies have lately been developed using vario...
متن کاملCharacterization and Cytocompatibility of Doxycycline Composite Scaffolds
510 ©2011 Society For Biomaterials
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Tissue Engineering Part C: Methods
سال: 2016
ISSN: 1937-3384,1937-3392
DOI: 10.1089/ten.tec.2015.0439